MORF4L1 anticorps (N-Term)
Aperçu rapide pour MORF4L1 anticorps (N-Term) (ABIN487997)
Antigène
Voir toutes MORF4L1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- APKQDPKPKF QEG-C
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Specificité
- This antibody recognizes MRG15 and is expected to recognise Isoform 1 (NP_006782.1) and Isoform 2 (NP_996670.1).
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Porcine, Bovine.
Species reactivity (tested):Human. -
Purification
- Affinity Chromatography
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Immunogène
- Syntehtic peptide from the N-Terminus of Human MORF4L1 (NP_006782.1, NP_996670.1) . Genename: MORF4L1
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Indications d'application
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Peptide ELISA: 1/64000. Western blot: Preliminary experiments gave an approx 40 kDa band in Human Liver lysatesand an approx 100 kDa band in Human Heart lysates at 1 μg/mL. Please note that currentlywe cannot find an explanation in the literature for the bands we observe given thecalculated size of 37.0 kDda according to NP_006782.1. Immunohistochemistry on paraffin sections: Human Uterus shows nuclear staining in theepithelial cells of the endometrial glands. Recommended concentration: 2 - 4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))
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Autre désignation
- MRG15
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Sujet
- MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.Synonyms: FWP006, HSPC008, HSPC061, MORF-related gene 15 protein, MORF4L1, MRG15, MSL3-1 protein, Mortality factor 4-like protein 1, PP368, Transcription factor-like protein MRG15
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Poids moléculaire
- 37.2 kDa (Mouse NP_077751.1).
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ID gène
- 10933
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NCBI Accession
- NP_006782
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UniProt
- Q9UBU8
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Pathways
- Chromatin Binding
Antigène
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